China Antimitotic Drug MMAF 745017-94-1,Antimitotic Drug MMAF 745017-94-1 Manufacturer
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Antineoplastic Agent MMAF Cas No. 745017-94-1
Thera. Category: Antineoplastic
Cas No.:745017-94-1
Synonyms: HM-297C-22;MonoMethyl auristatin E (MMAE);N-Methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide;N-Methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide Monomethyl;MonoMethyl auristatin E;MMAE;Vedotin;MonoMethyl auristatin E(MMAE, vedotin)
Molecular Formula:C39H65N5O8
Molecular Weight: 731.96
Purity: ≥99%
Packing: Export worthy packing
Material Safety Data Sheet: Available on request
Usage: Monomethyl auristatin F (MMAF) CAS 745017-94-1 is a synthetic antineoplastic agent.[1] It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody.
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