1195768-06-9,High Purity Dabrafenib Mesylate

We are professional 1195768-06-9,High Purity Dabrafenib Mesylate manufacturers and suppliers in China. These high quality products are formulated by adopting quality methods and using well-tested ingredients that are procured from the certified vendors of the market. We offer these products in proper packaging of diverse quantity to meet assorted requirements of the clients.

l Thera. Category:Anti- cancer

l Cas No.: 1195768-06-9

l Synonym:Dabrafenib Mesylate(GSK-2118436B);Dabrafenib Mesylate;GSK 2118436 Mesylate;GSK 2118436B;GSK2118436 Mesylate;GSK-2118436 Mesylate;Dabrafenib Mesylate (API);GSK 2118436 methanesulfonate salt

l Molecular Formula:C24H24F3N5O5S3

l Molecular Weight:615.6680696

l Assay: ≥97.%

l Packing:Export worthy packing

l Material Safety Data Sheet:Available on request

l Usage: Dabrafenib, also known as GSK2118436, is an orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B-raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B-raf belongs to the the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which may be constitutively activated due to BRAF gene mutations. On May 29, 2013, FDA approved this drug.

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